Coenzyme A and its role in Maintaining Cardiovascular Health

by Nickolaos D. Skouras, PhD.

Heart disease is the leading cause of death in the United States. Clogged arteries (atherosclerosis) can set the stage for life threatening heart attacks. What causes clogged arteries? Researchers believe that when LDL cholesterol in the bloodstream is oxidized by free radical attack, it tends to build up as plaque on the walls of blood vessels, impacting the free flow of blood. To further complicate matters, "sticky" blood platelets can clot inside damaged arteries, further cutting off blood flow supply to the heart.

Published research shows that a deficiency of metabolic enzymes exists globally specifically the "Master Coenzyme, Coenzyme-A". Coenzyme-A is the most active metabolic enzyme in the human body. It operates in the body's cells and blood where it initiates over 100 crucial biological functions in the body. Coenzyme-A acts as the "universal catalyst"; it is the primary biological cofactor used in acyl group transfers. Coenzyme-A initiates the fatty acid metabolism that breaks down and degrades the long molecular chains of fatty acids by adding or removing acyl groups. This process has significant lipid (fat) lowering activity that inhibits the synthesis of fatty acids into cholesterol and triglycerides and it also accelerates the utilization of fatty acids as an energy source.

Further studies show that the problems most people have with metabolizing fat are often the result of poor nutrition, which is usually compounded by poisoning from environmental toxins. Coenzyme-A is among the more vulnerable targets for toxic metals prescription drugs and fat-soluble environmental toxins. Individuals who have a shortage or blockage of Coenzyme-A cannot convert dietary lipids (fats) from animals and plants into human fat compositions that can be metabolized and converted to essential fatty acids. If fat cannot be metabolized due to a shortage or blockage of Coenzyme-A then the fat simply accumulates. Having accumulated fat deposits that cannot be metabolized and converted into energy leads to cardiovascular disease, stress, low energy, depression, anxiety, chronic fatigue, obesity and manifestations of other disease conditions.

Coenzyme-A is also required to initiate the tricarboxylic acid (TCA) cycle and metabolize fat, carbohydrates, and protein and convert them into cellular energy. The TCA cycle produces more than 90% of the energy the body requires to sustain life. Coenzyme-A is constantly being expended by the over demand of metabolic processes of the human body and constantly needs replenishing. The Most Recent Published Research shows that:

According to Phyllis A. Balch, CNC and James F. Balch, MD. in the ( THIRD EDITION ) of the best selling nutritional guide to natural health "Prescription for NUTRITIONAL HEALING." Coenzyme -A, by Coenzyme -A Technologies, Inc. Reduces free radical damage to LDL cholesterol and decreases human platelet aggregation by supporting the immune systems detoxification of many dangerous substances. It provides an all -natural way to maintain the healthy, normal functioning of the heart and the whole cardiovascular system.

In summary, proper nutrition and a healthy diet, combined with Coenzyme-A, a natural vitamin and mineral supplement, clean fresh air and exercise, may be the best prescription for improving the way your body looks and feels and for providing superior "health insurance" for long life.

REFERENCES:

  1. Abiko Y.; Metabolism ofCoenzyme-A; New York Academic Press, Third Edition 1975; 7:1-25.
  2. Knight, G. D., Ph.D.; A Waist is a terrible thing to mind; 1998.
  3. Leung, L. H., M.D.; Pantothenic Acid as a Weight Reducing Agent: Fasting Without Hunger, Weakness and Ketosis; 1995; 44, 403, 405.
  4. Robishaw, J. D. & Neely, J. R.; Coenzyme A Metabolism; American Journal of Physiology 1985; 248: El- E9.
  5. Kunz, J. R. M., M.D.; The American Medical Association, Family Medical Guide; Random House Inc.; 1982.
  6. Masoro, E. J.; Lipids and Lipid Metabolism; Annual Review of Physiology 1977; 39-301-21.
  7. Stumpf, P. K.; Metabolism of Fatty Acids; Annual Review of Biochemistry 1969; 38-159-212.
  8. Krebs, H. A.; The Regulation of Release ofKetone Bodies By the Liver; Advanced Enzyme Reaction 1966; 4: 339-354.
  9. Grenville, G. D. & Tubbs, P. K.; The Catabolism of Long-Chain Fatty Acids; Essays in Biochemistry 1969; 4-155-212.