The Structure of Pantothenic Acid and Coenzyme-A

by Nickolaos D. Skouras, PhD.

Pantothenic acid is an oil which is required by humans, animals and some micro-organisms. Pantothenic acid is a member of the Vitamin B group and is a constituent of Coenzyme-A

Coenzyme-A is involved in many acyl group transfer reaction pathways in the body. Importantly it is involved in the formation of fatty acids, polyketides and the synthesis of terpeniods and steroids. Structurally Coenzyme-A is composed of adenosine-3', 5'-diphosphate and pantetheine phosphate. Pantetheine itself is made from pantothenic acid and mercaptoethylamine.